Application Note: Differential Fab Binding to GORE® Protein Capture Devices A detailed application note demonstrates how GORE® Protein Capture Devices with Protein A show differential Fab fragment binding based on VH3 residue 57 mutations—guiding antibody design for improved capture, yield and purification workflows. See more
Application Note: Evaluation of Dynamic Binding Capacity and Residence Time of Membrane-Based GORE® Protein Capture Device with Protein A Boehringer-Ingelheim testing showed GORE® Protein Capture Devices with Protein A can cut process time and boost yields in monoclonal antibody purification. Unlike agarose bead columns, Gore’s devices may eliminate extra downstream concentration steps for greater efficiency. See more
Application Note: Extended Cycling Durability, High Productivity Membrane-Based Affinity Purification using GORE® Protein Capture Devices with Protein A This application note provides data demonstrating high productivity, extended cycling durability performance of membrane-based GORE® Protein Capture Devices with Protein A across two rapid Clean-in-Place methods bracketing caustic contact time and concentration. See more
Application Note: GORE® Protein Capture Devices: Increased Productivity at Multiple Scales with Rapid CIP This application note demonstrates utilizing a rapid CIP and optimizing the loading and non-loading residence times during cycling to achieve increased productivity on a Gore Protein Capture Device. See more
Application Note: Increase Productivity with a Simulated Moving Bed Chromatography Technique Evaluate the GORE® Protein Capture Device with Protein A combined with a simulated moving bed chromatography technique, CaptureSMB(TM), to increase the productivity of IgG purification. A joint study with Athena Enzyme Systems and Gore & Associates. See more
Application Note: Rapid Cycling using the GORE® Protein Capture Device with Protein A, 58 mL for Clinical Applications Evaluation of the 58 mL GORE® Protein Capture Device (PROA201) with clarified CHO cell harvest showed higher productivity by increasing non-loading flow rates while maintaining yield, purity, and elution widths—ensuring consistent quality in bioprocessing. See more
Application Note: Sodium Hydroxide (NaOH) Exposure Conditions for Successful Operation of GORE® Protein Capture Devices with Protein A for Drug Discovery Applications Data shows the 1.0 mL and 3.5 mL GORE® Protein Capture Devices (PROA101, PROA102) withstand up to 50 purification cycles with 0.5 M NaOH. Even after repeated sodium hydroxide exposure, they maintain yield, capacity, and purity—supporting efficient Protein A chromatography. See more
Application Questionnaire: GORE® LYOGUARD® Freeze-Drying Trays Do you have questions about GORE LYOGUARD Freeze-Drying Trays? It is important for us to understand how the trays will be used so that we can ensure compliance with industry standards as well as those of our own qualification process. See more
Article: Electric Vehicles' Innovation, and the Human Element in Venting Solutions Engineering knowledge, simulation software, and testing practices are powerful tools when coupled with human connection. See more
Article: "What a Drag" Addresses the Benefits of Installing Filter Bags with the Lowest Drag By installing filter bags with the lowest possible filter drag, cement producers will be able to choose their desired benefit of either 1) fan energy savings, 2) increased airflow, 3) longer filter bag life, or 4) decreased number of installed filter bags. See more