Application Note: Sodium Hydroxide (NaOH) Exposure Conditions for Successful Operation of GORE® Protein Capture Devices with Protein A for Drug Discovery Applications

Data shows the 1.0 mL and 3.5 mL GORE® Protein Capture Devices (PROA101, PROA102) withstand up to 50 purification cycles with 0.5 M NaOH. Even after repeated sodium hydroxide exposure, they maintain yield, capacity, and purity—supporting efficient Protein A chromatography.