GORE® LYOGUARD® Freeze-Drying Trays

Developed in consultation with the pharmaceutical lyophilization industry, GORE LYOGUARD Freeze-Drying Trays provide a cost-effective method of freeze-drying by containing product throughout the lyophilization process.

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Pharmaceutical & Biopharmaceutical

Gore’s rigorously compliant, technology-driven products and process components designed for efficiency, reliability and contamination control.

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Exceptional product protection and containment during lyophilization

The GORE LYOGUARD Freeze-Drying Tray was specifically engineered for use in applications ranging from bulk processing to formulation research and development, and from clinical phases to full-scale pharmaceutical and biopharmaceutical manufacturing, up to 1800 mls.  Gore trays are ideal for freeze-drying:

  • biologics
  • peptides
  • oligonucleotides
  • proteins
  • intermediate drug substance
  • API

Unique to this tray is its GORE™ Membrane — an integrated top barrier that delivers:

  • a high vapor transmission rate, so water and solvent vapors are readily released
  • highly-effective barrier protection, to minimize the risk of cross-contamination, limit exposure to API and reduce the chance of fly-out
Illustration shows how GORE™ ePTFE Membrane repels contaminants and allows vapor to escape.

Gore's unique ePTFE membrane enables high efficiency lyophilization yet provides a barrier to product cross-contamination.

Disposable, single-use trays save time
  • optimize throughput, with shorter cycle times
  • eliminate cleaning of trays and/or covers after use
  • covered tray reduces chance fly-out; averts spills and associated cleanups
Easily integrated with your processes
  • a direct replacement for open or covered trays or containers
  • convenient fill-cap for efficient filling operations
  • compatible with most freeze-drying processes and equipment
  • can be sterilized using autoclaving
Gore quality is assured
  • produced under relevant current Good Manufacturing Practices (cGMPs)
  • assembly operations are conducted in an ISO 8 clean room with particle monitoring to ensure operation to at least ISO 7 (Class 10,000)
  • final inspection and packaging are conducted in a controlled environment
  • 100% visual inspection for defects in workmanship and visible contamination


How it Works

The Performance Technology of the GORE LYOGUARD Freeze-Drying Tray

These disposable (single-use) trays incorporate innovative GORE Membrane technology and a unique design to make lyophilization processes easier, and more efficient, than other traditional containers.

Closeup of top of a GORE LYOGUARD Tray
The tray top

The tray top is an integrated GORE Membrane with a spout to make tray-filling easy and convenient. The GORE Membrane itself has a specialized microporous structure that is ideal for use in freeze-drying applications. It is engineered to optimize vapor transmission so water and solvents can escape readily. At the same time, this membrane provides excellent barrier protection so it simultaneously repels contaminants and minimizes the risk of fly-out.


SEM image of Lyoguard Tray ePTFE membrane
About the GORE Membrane

The surface of this 100% ePTFE membrane is engineered to be:

  • chemically inert
  • biocompatible
  • non-particulating
  • thermally stable



Closeup of base of a GORE LYOGUARD Tray
The Tray Base

The tray base of flexible thin film closely conforms to dryer shelves, for efficient and uniform heat transfer.

GORE LYOGUARD Freeze-Drying Trays provide the optimal balance of breathable vapor transmission and barrier protection. This ensures that your product remains properly contained and protected.


Product Comparison

Performance Advantages with Gore

The GORE LYOGUARD Freeze-Drying Tray is a unique replacement for open stainless-steel trays and other containers traditionally used for the lyophilization process. Neither open trays nor trays with improvised wraps or covers can match the unique combination of performance benefits that GORE LYOGUARD Freeze-Drying Trays provide.

Trays vs. Alternatives


Image of application questionnaire

It is important for us to understand how GORE LYOGUARD Freeze-Drying trays will be used so that we can ensure compliance with industry standards as well as those of our own qualification process. Please tell us more about your requirements and application by completing our Application Questionnaire.

Thank you for your consideration. We look forward to working with you.

For more general questions about our trays and their application, please contact us by email using the link below.


Recent News

Press Release

Gore Attending Two Upcoming Biopharmaceutical Conferences in April

Posted March 22, 2019

Visit Booth 70 at BPI Europe in Vienna and Booth 3737 at Interphex in New York City to learn how Gore's innovative technologies help biopharmaceutical manufacturers achieve efficiency and operate reliably.


Article: Lyophilization: The Basics

Posted October 23, 2017

Cherish Robinson, Product Specialist with Gore's PharmBIO business, discusses the advantages and disadvantages of freeze-drying bulk drug ingredients.

View all News & Events