Resource Library

The 9.0mL Device (PROA103) GORE Protein Capture Device provides performance advantages over traditional agarose resin columns in late stage discovery, pre-clinical and early clinical applications.

GORE Protein Capture Devices use a unique expanded polytetrafluorethylene (ePTFE) membrane composite that provides a binding capacity advantage at high flow rates to improve the speed of purification in drug discovery applications.

GORE Protein Capture Devices with Protein A are intended for the affinity purification of monoclonal antibodies and other proteins containing an Fc region derived from clarified cell culture harvests in process development to initial GMP clinical applications.

Engineered from the same materials of construction as the GORE STA-PURE Flexible Freeze Container, the 50-ml Stability container assembly is designed to support testing during drug substance development.

Single-use GORE® STA-PURE® Flexible Freeze Containers are intended for handling, transport and storage of frozen bulk drug substances after freezing at -86°C (-123°F).

Due to the worldwide response to COVID-19-related R&D; increased development of novel therapeutics; and the expansion of cell and gene therapy innovations, biopharma manufacturers are seeing significant manufacturing momentum.

For many emerging cell and gene therapies, their increasing sensitivity and how that may impact stability have made their storage and transport uniquely challenging. This complexity has led to pioneering new container technologies designed for increasingly complex biologics; while the space had been historically dominated by bottles, closed multilayer bag assemblies and, more recently, single-layer fluoropolymer bags have become the more attractive choice for companies with colder storage and transport temperature requirements.

GORE LYOGUARD Trays are fully enclosed, single-use, disposable containers that use a unique ePTFE membrane technology to both prevent cross contamination and fly-out, and enable the free exchange of moisture vapor during freeze-drying.

GORE LYOGUARD Freeze-Drying Trays are fully enclosed, single-use, disposable containers that use expanded polytetrafluoroethylene (ePTFE) membrane technology to contain and protect liquid or lyophilized active pharmaceutical ingredient (API) during the entire freezedrying process.

Cherish Robinson, Product Specialist with Gore's PharmBIO business, discusses the advantages and disadvantages of freeze-drying bulk drug ingredients.