Resource Library

This application note provides data demonstrating high productivity, extended cycling durability performance of membrane-based GORE Protein Capture Devices with Protein A across two rapid Clean-in-Place methods bracketing caustic contact time and concentration. These data were then combined with results from a manufacturing-scale demonstration to extrapolate protein capture capabilities at a 2000 L batch bioreactor size across CIP methods.

GORE AME-Clamps enable convenient flow metering or precise flow closure within tubing systems for bioprocessing operations. These lightweight single-use clamps are easy to install over tubing, and the locking screw is fully adjustable using just one hand.

Custom-configured GORE Molded Assemblies with the GORE Aseptic Sampling Valve offer bioprocess operators a way to streamline the collection of multiple aseptic samples from stainless steel vessels.

This application note demonstrates the scalability across multiple GORE Protein Capture Device sizes through dynamic binding capacity, CHO cell harvest, and purification experiments as demonstrated with a partially purified monoclonal antibody.

GORE® Microfiltration Media help design engineers and program managers of Original Equipment Manufacturers (OEMs) and Contract Development Manufacturing Organizations (CDMOs) of diagnostics equipment and consumables to develop molecular diagnostic (MDx) panels with consistent and precise fluid movement thus enabling accurate and reliable test results. Unlike other filter or vent options Gore’s vent solutions are engineered to work with aggressive reagents and solvents giving more degrees of freedom in cartridge design enabling the most cost-effective designs.

Describes the freeze profile of the GORE® STA-PURE® Flexible Freeze Container including the freeze methodology and the impact of the carrier on freeze performance.

This document is available upon request.

The 9.0mL Device (PROA103) GORE Protein Capture Device provides performance advantages over traditional agarose resin columns in late stage discovery, pre-clinical and early clinical applications.

General handling, antibody purification protocol and troubleshooting guide for PROA103.

General handling, antibody purification protocol, troubleshooting, and ordering information.

GORE Protein Capture Devices use a unique expanded polytetrafluorethylene (ePTFE) membrane composite that provides a binding capacity advantage at high flow rates to improve the speed of purification in drug discovery applications.