Resource Library

This application note provides data demonstrating high productivity, extended cycling durability performance of membrane-based GORE Protein Capture Devices with Protein A across two rapid Clean-in-Place methods bracketing caustic contact time and concentration. These data were then combined with results from a manufacturing-scale demonstration to extrapolate protein capture capabilities at a 2000 L batch bioreactor size across CIP methods.

This application note demonstrates the scalability across multiple GORE Protein Capture Device sizes through dynamic binding capacity, CHO cell harvest, and purification experiments as demonstrated with a partially purified monoclonal antibody.

Describes the freeze profile of the GORE® STA-PURE® Flexible Freeze Container including the freeze methodology and the impact of the carrier on freeze performance.

This document is available upon request.

General handling, antibody purification protocol and troubleshooting guide for PROA103.

General handling, antibody purification protocol, troubleshooting, and ordering information.

General handling, antibody purification protocol and troubleshooting guide for 58mL (PROA201), 116 mL (PROA202), 232 mL (PROA203), 250 mL (PROA301), 500 mL (PROA302), and 1L (PROA303).

This application note demonstrates utilizing a rapid CIP and optimizing the loading and non-loading residence times during cycling to achieve increased productivity on a Gore Protein Capture Device. The method is easily transferred from lab scale to pilot scale sizes as demonstrated using both PROA101 (1mL) and PROA201 (58 mL) Gore Protein Capture Devices.

Do you have questions about GORE LYOGUARD Freeze-Drying Trays? It is important for us to understand how the trays will be used so that we can ensure compliance with industry standards as well as those of our own qualification process.

Recommendations for tray handling during filling, dryer loading/unloading, product sampling and removing or reconstituting dried product.

Autoclave sterilization guidelines for GORE LYOGUARD Freeze-Drying Trays