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Request the Validation Guide for complete testing details for the GORE Protein Capture Device 58mL (PROA201), 116 mL (PROA202), and 232 mL (PROA203). This document is available upon request. English (U.S.) Chromatography Operating Instructions: GORE Protein Capture Device for 58mL, 116 mL, and 232 mL Technical Information, 161.48 KB General handling, antibody purification protocol and troubleshooting guide for 58mL (PROA201), 116 mL (PROA202), and 232 mL (PROA203). English (U.S.) Chromatography GORE® Protein Capture Device 58mL (PROA201), 116 mL (PROA202), and 232 mL (PROA203) Data Sheets, 316.97 KB GORE Protein Capture Devices with Protein A are intended for the affinity purification of monoclonal antibodies and other proteins containing an Fc region derived from clarified cell culture harvests in process development to initial GMP clinical applications. English (U.S.) Chromatography Application Note: Rapid Cycling using the GORE® Protein Capture Device with Protein A, 58 mL for Clinical Applications Technical Information, 416.71 KB This evaluation demonstrates a method to improve productivity by increasing flow rates for the non-loading steps with a representative clarified CHO cell harvest with the 58mL, GORE Protein Capture Device (PROA201) and maintaining critical quality attributes including yield, purity and elution widths. English (U.S.) Chromatography Operating Instructions: GORE® Protein Capture Devices for Drug Discovery Applications Technical Information, 161.64 KB General handling, antibody purification protocol, troubleshooting, and ordering information. English (U.S.) Chromatography Validation Guide: GORE® Protein Capture Devices Validation Guides Designed for small-scale affinity purification of monoclonal antibodies, GORE Protein Capture Devices provide high binding capacity at short residence time with the potential for fewer process steps. This document is available upon request. English (U.S.) Chromatography Data Sheet: GORE® Protein Capture Devices Data Sheets, 233.05 KB GORE Protein Capture Devices use a unique expanded polytetrafluorethylene (ePTFE) membrane composite that provides a binding capacity advantage at high flow rates to improve the speed of purification in drug discovery applications. English (U.S.) Chromatography Application Note: Alternative Method for mAb Purification; Rapid Purification without a Liquid Chromatography Unit using a GORE® Protein Capture Device Technical Information, 338.72 KB The GORE Protein Capture Device with Protein A can be used as demonstrated in three different manual/semi-automated operations to rapidly purify monoclonal antibodies without an LC unit. English (U.S.) Chromatography Application Note: Evaluation of 3.5 mL GORE® Protein Capture Devices Used in Series for Monoclonal Antibody Purification Technical Information, 177.2 KB Two 3.5 mL GORE Protein Capture Devices can be connected in series, which doubles the column capacity by providing a 7.0 mL bed volume and allows capture of at least 200 mg of monoclonal antibody within 60 minutes. English (U.S.) Medical OEM White Paper: A Commitment to Manufacturing Quality as the New Competitive Edge White Papers A discussion on how new updates to quality standards encourage medical device manufacturers to expect more from their upstream component suppliers. This document is available upon request: English (U.S.) Load more resources