Lyophilization in the Pharmaceutical and Biotechnology Industries

For more than 50 years, lyophilization — or freeze-drying — has been an effective method used in laboratory and commercial production for stabilizing and preserving valuable, heat-sensitive products. Products commonly preserved by lyophilization include: pharmaceutical and biotechnology drug formulations, blood plasma, bacteria and other microorganisms. Lyophilization and freeze-drying are synonymous terms and can be used interchangeably.

The key concept of lyophilization is sublimation – a process where a substance changes from a solid to a vapor without passing through a liquid phase. When comparing freeze-dried products with their liquid counterparts, they have:

• Longer shelf life
• Less cumbersome storage, handling and distribution requirements
• Lower shipping costs because of reduced weight, especially for bulk applications
• Reduced need for cold storage environments

Stabilize liquid drug formulations and/or parenterals through lyophilization
The process of freeze-drying is used often to stabilize delicate and heat-sensitive materials and compounds such as:

Products for the next generation of lyophilization
GORE™ LYOGUARD® Freeze-Drying Products have modernized the way in which the pharmaceutical and biotechnology industries process drugs providing unique solutions to the sterility and processing challenges of lyophilization.

Need more information?
Visit the GORE™ LYOGUARD FAQ section or Contact us for more information or to discuss your next pharmaceutical processing opportunity.